“Lithium forms a complex with the ammonia molecule, and since ammonia mimics the effects of serotonin, especially in fatigue, this could be involved in lithium’s anti-serotonergic effects. Ammonia, like serotonin, impairs mitochondrial energy production (at a minimum, it uses energy in being converted to urea), so anti-ammonia anti-serotonin agents make more energy available for adaptation.” -Ray Peat